Ontology highlight
ABSTRACT:
SUBMITTER: Braud VM
PROVIDER: S-EPMC5927544 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Braud Véronique M VM Biton Jérôme J Becht Etienne E Knockaert Samantha S Mansuet-Lupo Audrey A Cosson Estelle E Damotte Diane D Alifano Marco M Validire Pierre P Anjuère Fabienne F Cremer Isabelle I Girard Nicolas N Gossot Dominique D Seguin-Givelet Agathe A Dieu-Nosjean Marie-Caroline MC Germain Claire C
Oncoimmunology 20180129 5
Co-stimulatory and inhibitory receptors expressed by immune cells in the tumor microenvironment modulate the immune response and cancer progression. Their expression and regulation are still not fully characterized and a better understanding of these mechanisms is needed to improve current immunotherapies. Our previous work has identified a novel ligand/receptor pair, LLT1/CD161, that modulates immune responses. Here, we extensively characterize its expression in non-small cell lung cancer (NSCL ...[more]