Ontology highlight
ABSTRACT:
SUBMITTER: Kan Z
PROVIDER: S-EPMC5928087 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Nature communications 20180430 1
Breast cancer (BC) in the Asia Pacific regions is enriched in younger patients and rapidly rising in incidence yet its molecular bases remain poorly characterized. Here we analyze the whole exomes and transcriptomes of 187 primary tumors from a Korean BC cohort (SMC) enriched in pre-menopausal patients and perform systematic comparison with a primarily Caucasian and post-menopausal BC cohort (TCGA). SMC harbors higher proportions of HER2+ and Luminal B subtypes, lower proportion of Luminal A wit ...[more]