Ontology highlight
ABSTRACT:
SUBMITTER: Gomez-Llorente MA
PROVIDER: S-EPMC7555790 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Gomez-Llorente Mª Amelia MA Martínez-Cañavate Ana A Chueca Natalia N Rico Mª de la Cruz MC Romero Raquel R Anguita-Ruiz Augusto A Aguilera Concepción Mª CM Gil-Campos Mercedes M Mesa Maria D MD Khakimov Bekzod B Morillo Jose Antonio JA Gil Ángel Á Camacho José J Gomez-Llorente Carolina C
Biomedicines 20200918 9
<b>Background:</b> Asthma is a multifactorial condition where patients with identical clinical diagnoses do not have the same clinical history or respond to treatment. This clinical heterogeneity is reflected in the definition of two main endotypes. We aimed to explore the metabolic and microbiota signatures that characterize the clinical allergic asthma phenotype in obese children. <b>Methods:</b> We used a multi-omics approach combining clinical data, plasma and fecal inflammatory biomarkers, ...[more]