Ontology highlight
ABSTRACT:
SUBMITTER: Waltmann A
PROVIDER: S-EPMC5928730 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Waltmann Andreea A Patel Jaymin C JC Thwai Kyaw L KL Hathaway Nicholas J NJ Parobek Christian M CM Massougbodji Achille A Fievet Nadine N Bailey Jeffery A JA Deloron Philippe P Juliano Jonathan J JJ Ndam Nicaise Tuikue NT Meshnick Steven R SR
The American journal of tropical medicine and hygiene 20180101 1
In pregnancy-associated malaria, infected erythrocytes accumulate in the placenta. It is unclear if in polyclonal infections this results in distinct peripheral and placental parasite populations. We used long amplicon deep sequencing of <i>Plasmodium falciparum var2csa</i> ID1-DBL2X from 15 matched peripheral and placental samples collected at delivery from a high transmission area to determine genetic homology. Despite substantial sequence variation and detecting 23 haplotypes, the matched pai ...[more]