Ontology highlight
ABSTRACT:
SUBMITTER: Veenstra CM
PROVIDER: S-EPMC5929883 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Veenstra Christine M CM Krauss John C JC
Clinics in colon and rectal surgery 20180401 3
Despite advances over the past 20 years in colorectal cancer (CRC) screening, diagnosis, and treatment, survival outcomes remain suboptimal. Five-year survival for patients with locally advanced CRC is 69%; 5-year survival drops to 12% for patients with metastatic disease. Novel, effective systemic therapies are needed to improve long-term outcomes. In this review, we describe currently available systemic therapies for the treatment of locally advanced and metastatic CRC and discuss emerging the ...[more]