Ontology highlight
ABSTRACT:
SUBMITTER: Wang B
PROVIDER: S-EPMC5930468 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
International journal of medical sciences 20180403 6
Hepatocellular carcinoma (HCC) is a liver malignancy and a major cause of cancer mortality worldwide. Matrix metalloproteinase-11 (MMP-11), also known as stromelysin-3, plays a critical role during tumor migration, invasion and metastasis. Here, we report on the association between five single nucleotide polymorphisms (SNPs) - rs738791, rs2267029, rs738792, rs28382575, and rs131451 - of the <i>MMP-11</i> gene and HCC susceptibility, as well as clinical outcomes, in 293 patients with HCC and in 5 ...[more]