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Transcriptional analysis of liver from chickens with fast (meat bird), moderate (F1 layer x meat bird cross) and low (layer bird) growth potential.


ABSTRACT: BACKGROUND:Divergent selection for meat and egg production in poultry has resulted in strains of birds differing widely in traits related to these products. Modern strains of meat birds can reach live weights of 2 kg in 35 d, while layer strains are now capable of producing more than 300 eggs per annum but grow slowly. In this study, RNA-Seq was used to investigate hepatic gene expression between three groups of birds with large differences in growth potential; meat bird, layer strain as well as an F1 layer x meat bird. The objective was to identify differentially expressed (DE) genes between all three strains to elucidate biological factors underpinning variations in growth performance. RESULTS:RNA-Seq analysis was carried out on total RNA extracted from the liver of meat bird (n =?6), F1 layer x meat bird cross (n =?6) and layer strain (n =?6), males. Differential expression of genes were considered significant at P 

SUBMITTER: Willson NL 

PROVIDER: S-EPMC5930858 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Transcriptional analysis of liver from chickens with fast (meat bird), moderate (F1 layer x meat bird cross) and low (layer bird) growth potential.

Willson Nicky-Lee NL   Forder Rebecca E A REA   Tearle Rick R   Williams John L JL   Hughes Robert J RJ   Nattrass Greg S GS   Hynd Philip I PI  

BMC genomics 20180502 1


<h4>Background</h4>Divergent selection for meat and egg production in poultry has resulted in strains of birds differing widely in traits related to these products. Modern strains of meat birds can reach live weights of 2 kg in 35 d, while layer strains are now capable of producing more than 300 eggs per annum but grow slowly. In this study, RNA-Seq was used to investigate hepatic gene expression between three groups of birds with large differences in growth potential; meat bird, layer strain as  ...[more]

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