Ontology highlight
ABSTRACT:
SUBMITTER: Li R
PROVIDER: S-EPMC5931146 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Li Rui R Ma Hongfang H Jiang Longguang L Qiao Songlin S Zhi Yubao Y Huang Mingdong M Deng Ruiguang R Zhang Gaiping G
Acta crystallographica. Section F, Structural biology communications 20180425 Pt 5
Scavenger receptors (SRs) play critical roles in various physiological and pathological pathways. One of them, CD163, is a multifunctional endocytic receptor and is characterized by a long-range scavenger receptor cysteine-rich (SRCR) repeat. However, the structural and functional details of this long-range SRCR repeat have not yet been elucidated. In this study, the CD163 long-range SRCR repeat was expressed in Drosophila Schneider 2 cells. The recombinant protein was homogeneous after purifica ...[more]