Ontology highlight
ABSTRACT:
SUBMITTER: Sun M
PROVIDER: S-EPMC5932762 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Sun Mengying M Vazquez Ana I AI Reynolds Richard J RJ Singh Jasvinder A JA Reeves Mathew M Merriman Tony R TR Gaffo Angelo L AL Los Campos Gustavo de G
Arthritis research & therapy 20180503 1
<h4>Background</h4>Many gout comorbidities (e.g., hypertension) are correlated with serum urate. In this investigation, we identified risk factors (e.g., systolic blood pressure [SBP]), that (1) are associated with incident gout, (2) have effects on gout risk that cannot be fully explained by correlated differences in serum urate, and (3) may modulate the relationship between gout and serum urate.<h4>Methods</h4>Using data from the Atherosclerosis Risk in Communities (ARIC) study, we estimated t ...[more]