Ontology highlight
ABSTRACT:
SUBMITTER: Han P
PROVIDER: S-EPMC5934567 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Han Pengxun P Shao Mumin M Guo Lan L Wang Wenjing W Song Gaofeng G Yu Xuewen X Zhang Chunlei C Ge Na N Yi Tiegang T Li Shunmin S Du Heng H Sun Huili H
American journal of translational research 20180415 4
Diabetes and its renal complications are major medical challenges worldwide. There are no effective drugs currently available for treating diabetes and diabetic kidney disease (DKD), especially in type 1 diabetes (T1D). Evidence has suggested that niclosamide ethanolamine salt (NEN) could improve diabetic symptoms in mice of type 2 diabetes (T2D). However, its role in T1D and DKD has not been studied to date. Here we report that NEN could protect against diabetes in streptozotocin (STZ) induced ...[more]