Ontology highlight
ABSTRACT:
SUBMITTER: Huang L
PROVIDER: S-EPMC5937300 | biostudies-literature | 2018 Jan-Mar
REPOSITORIES: biostudies-literature
Huang Lei L Boling Warren W Zhang John H JH
Medical gas research 20180101 1
Glioblastoma multiforme (GBM) is the most common type of malignant intracranial tumor in adults. Tumor tissue hypoxia, high mitotic rate, and rapid tumor spread account for its poor prognosis. Hyperbaric oxygen therapy (HBOT) may improve the sensitivity of radio-chemotherapy by increasing oxygen tension within the hypoxic regions of the neoplastic tissue. This review summarizes the research of HBOT applications within the context of experimental and clinical GBM. Limited clinical trials and prec ...[more]