Ontology highlight
ABSTRACT:
SUBMITTER: He Z
PROVIDER: S-EPMC5938701 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
He Zhongyuan Z Li Zheng Z Zhang Xuan X Yin Kai K Wang Weizhi W Xu Zhipeng Z Li Bowen B Zhang Lei L Xu Jianghao J Sun Guangli G Wang Lu L Li Qing Q Huang Xiaoxu X Zhang Lu L Zhang Diancai D Xu Hao H Xu Zekuan Z
Cell death & disease 20180501 5
Increasing evidence indicates that dysregulation of microRNAs (miRNAs) plays a crucial role in human malignancies. Here, we showed that microRNA-422a (miR-422a) expression was dramatically downregulated in gastric cancer (GC) samples and cell lines compared with normal controls, and that its expression level was inversely related to tumor size and depth of infiltration. Functional studies revealed that the overexpression of miR-422a in GC tumor cells suppressed cell proliferation and migration, ...[more]