Ontology highlight
ABSTRACT:
SUBMITTER: Davis P
PROVIDER: S-EPMC5940487 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Davis Patrick P Zaki Yosif Y Maguire Jamie J Reijmers Leon G LG
Nature neuroscience 20171002 11
The mammalian brain contains dedicated circuits for both the learned expression and suppression of fear. These circuits require precise coordination to facilitate the appropriate expression of fear behavior, but the mechanisms underlying this coordination remain unclear. Using a combination of chemogenetics, activity-based neuronal-ensemble labeling and in vivo electrophysiology, we found that fear extinction learning confers on parvalbumin-expressing (PV) interneurons in the basolateral amygdal ...[more]