Ontology highlight
ABSTRACT:
SUBMITTER: Brookes C
PROVIDER: S-EPMC5940884 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Brookes Charlotte C Freire-Martin Irene I Cavell Breeze B Alexander Frances F Taylor Stephen S Persaud Ruby R Fry Norman N Preston Andrew A Diavatopoulos Dimitri D Gorringe Andrew A
Emerging microbes & infections 20180509 1
Whooping cough is a re-emerging respiratory tract infection. It has become clear that there is a need for better understanding of protective immune responses and variation between Bordetella pertussis strains to aid the development of improved vaccines. In order to survive in the host, B. pertussis has evolved mechanisms to evade complement-mediated killing, including the ability to bind complement-regulatory proteins. Here we evaluate the variation in interactions with the complement system amo ...[more]