Ontology highlight
ABSTRACT:
SUBMITTER: Lastowska M
PROVIDER: S-EPMC5942343 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Łastowska Maria M Trubicka Joanna J Niemira Magdalena M Paczkowska-Abdulsalam Magdalena M Karkucińska-Więckowska Agnieszka A Kaleta Magdalena M Drogosiewicz Monika M Perek-Polnik Marta M Krętowski Adam A Cukrowska Bożena B Grajkowska Wiesława W Dembowska-Bagińska Bożenna B Matyja Ewa E
Journal of neuro-oncology 20180209 2
Medulloblastoma, the most common malignant pediatric brain tumor, is a heterogeneous disease, with the existence of at least four molecular types: Wingless (WNT), Sonic Hedgehog (SHH), Group 3 and Group 4 tumors. The latter two groups, which can be identified by an application of multi-gene expression or methylation profiling, show sometimes ambiguous categorization and are still classified for diagnostic reason as non-SHH/non-WNT medulloblastomas in updated WHO 2016 classification. In order to ...[more]