Ontology highlight
ABSTRACT:
SUBMITTER: Neubauer PR
PROVIDER: S-EPMC5945002 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Neubauer Pia R PR Widmann Christiane C Wibberg Daniel D Schröder Lea L Frese Marcel M Kottke Tilman T Kalinowski Jörn J Niemann Hartmut H HH Sewald Norbert N
PloS one 20180510 5
Flavin-dependent halogenases catalyse halogenation of aromatic compounds. In most cases, this reaction proceeds with high regioselectivity and requires only the presence of FADH2, oxygen, and halide salts. Since marine habitats contain high concentrations of halides, organisms populating the oceans might be valuable sources of yet undiscovered halogenases. A new Hidden-Markov-Model (HMM) based on the PFAM tryptophan halogenase model was used for the analysis of marine metagenomes. Eleven metagen ...[more]