Ontology highlight
ABSTRACT:
SUBMITTER: Davidson NM
PROVIDER: S-EPMC5946861 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Davidson Nadia M NM Oshlack Alicia A
GigaScience 20180501 5
<h4>Background</h4>RNA sequencing (RNA-seq) analyses can benefit from performing a genome-guided and de novo assembly, in particular for species where the reference genome or the annotation is incomplete. However, tools for integrating an assembled transcriptome with reference annotation are lacking.<h4>Findings</h4>Necklace is a software pipeline that runs genome-guided and de novo assembly and combines the resulting transcriptomes with reference genome annotations. Necklace constructs a compac ...[more]