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A Novel "Off-On" Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging.

ABSTRACT: A novel fluorescent "off-on" probe based on carbon nitride (C?N?) nanoribbons was developed for citrate anion (C?H?O?^3-) detection. The fluorescence of C?N? nanoribbons can be quenched by Cu²⁺ and then recovered by the addition of C?H?O?^3-, because the chelation between C?H?O?^3- and Cu²⁺ blocks the electron transfer between Cu²⁺ and C?N? nanoribbons. The turn-on fluorescent sensor using this fluorescent "off-on" probe can detect C?H?O?^3- rapidly and selectively, showing a wide detection linear range (1~400 ?M) and a low detection limit (0.78 ?M) in aqueous solutions. Importantly, this C?N? nanoribbon-based "off-on" probe exhibits good biocompatibility and can be used as fluorescent visualizer for exogenous C?H?O?^3- in HeLa cells.

SUBMITTER: Hu Y

PROVIDER: S-EPMC5948658 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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A Novel "Off-On" Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging.

Hu Yanling Y Yang Donlgliang D Yang Chen C Feng Ning N Shao Zhouwei Z Zhang Lei L Wang Xiaodong X Weng Lixing L Luo Zhimin Z Wang Lianhui L

Sensors (Basel, Switzerland) 20180411 4

A novel fluorescent "off-on" probe based on carbon nitride (C₃N₄) nanoribbons was developed for citrate anion (C₆H₅O₇3-) detection. The fluorescence of C₃N₄ nanoribbons can be quenched by Cu2+ and then recovered by the addition of C₆H₅O₇3-, because the chelation between C₆H₅O₇3- and Cu2+ blocks the electron transfer between Cu2+ and C₃N₄ nanoribbons. The turn-on fluorescent sensor using this fluorescent "off-on" probe can detect C ...[more]

PMID: 29641452

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