Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Lorenzo D
PROVIDER: S-EPMC5951011 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
García-Lorenzo Daniel D Lavisse Sonia S Leroy Claire C Wimberley Catriona C Bodini Benedetta B Remy Philippe P Veronese Mattia M Turkheimer Federico F Stankoff Bruno B Bottlaender Michel M
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20170209 2
There is a great need for a non-invasive methodology enabling the quantification of translocator protein overexpression in PET clinical imaging. [<sup>18</sup>F]DPA-714 has emerged as a promising translocator protein radiotracer as it is fluorinated, highly specific and returned reliable quantification using arterial input function. Cerebellum gray matter was proposed as reference region for simplified quantification; however, this method cannot be used when inflammation involves cerebellum. Her ...[more]