Ontology highlight
ABSTRACT:
SUBMITTER: Putney JW
PROVIDER: S-EPMC5955777 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Advances in biological regulation 20171122
Calcium signals arise by multiple mechanisms, including mechanisms of release of intracellular stored Ca<sup>2+</sup>, and the influx of Ca<sup>2+</sup> through channels in the plasma membrane. One mechanism that links these two sources of Ca<sup>2+</sup> is store-operated Ca<sup>2+</sup> entry, the most commonly encountered version of which involves the extensively studied calcium-release-activated Ca<sup>2+</sup> (CRAC) channel. The minimal and essential molecular components of the CRAC channe ...[more]