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Association between obesity with disease-free survival and overall survival in triple-negative breast cancer: A meta-analysis.

ABSTRACT:

Objective

To investigate the relationship between obesity and disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer.

Methods

Citations were searched in PubMed, Cochrane Library, and Web of Science. Random effect model meta-analysis was conducted by using Revman software version 5.0, and publication bias was evaluated by creating Egger regression with STATA software version 12.

Results

Nine studies (4412 patients) were included for DFS meta-analysis, 8 studies (4392 patients) include for OS meta-analysis. There were no statistical significances between obesity with DFS (P?=?.60) and OS (P?=?.71) in triple-negative breast cancer (TNBC) patients.

Conclusion

Obesity has no impact on DFS and OS in patients with TNBC.

SUBMITTER: Mei L

PROVIDER: S-EPMC5959383 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Publications

Association between obesity with disease-free survival and overall survival in triple-negative breast cancer: A meta-analysis.

Mei Lin L He Lin L Song Yuhua Y Lv Yang Y Zhang Lijiu L Hao Fengxi F Xu Mengmeng M

Medicine 20180501 19

<h4>Objective</h4>To investigate the relationship between obesity and disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer.<h4>Methods</h4>Citations were searched in PubMed, Cochrane Library, and Web of Science. Random effect model meta-analysis was conducted by using Revman software version 5.0, and publication bias was evaluated by creating Egger regression with STATA software version 12.<h4>Results</h4>Nine studies (4412 patients) were included for DFS meta-a ...[more]

PMID: 29742734

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