Phosphorylated eIF2? predicts disease-free survival in triple-negative breast cancer patients.
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ABSTRACT:
SUBMITTER: Guo L
PROVIDER: S-EPMC5353635 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Phosphorylated eIF2α predicts disease-free survival in triple-negative breast cancer patients.
Guo Liang L Chi Yayun Y Xue Jingyan J Ma Linxiaoxi L Shao Zhiming Z Wu Jiong J
Scientific reports 20170315
Phosphorylated eukaryotic translation initiation factor 2α (p-eIF2α), which functions as a marker of endoplasmic reticulum stress, has been reported to be associated with patient prognosis in various cancers. However, little is known about the prognostic value of p-eIF2α in breast cancer, particularly in different breast cancer subtypes. An immunohistochemistry screen for p-eIF2α was performed using a tissue microarray containing 233 tumors and paired peritumoral tissues from female patients dia ...[more]
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