Ontology highlight
ABSTRACT:
SUBMITTER: Milak MS
PROVIDER: S-EPMC5959803 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Milak Matthew S MS Pantazatos Spiro S Rashid Rain R Zanderigo Francesca F DeLorenzo Christine C Hesselgrave Natalie N Ogden R Todd RT Oquendo Maria A MA Mulhern Stephanie T ST Miller Jeffrey M JM Burke Ainsley K AK Parsey Ramin V RV Mann J John JJ
Psychiatry research. Neuroimaging 20180413
Higher serotonin-1A (5-HT<sub>1A</sub>) receptor binding potential (BP<sub>F</sub>) has been found in major depressive disorder (MDD) during and between major depressive episodes. We investigated whether higher 5-HT<sub>1A</sub> binding is a biologic trait transmitted to healthy high risk (HR) offspring of MDD probands. Data were collected contemporaneously from: nine HR, 30 depressed not-recently medicated (NRM) MDD, 18 remitted NRM MDD, 51 healthy volunteer (HV) subjects. Subjects underwent po ...[more]