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Association between dipstick proteinuria and hearing impairment in health check-ups among Japanese workers: a cross-sectional study.

ABSTRACT: OBJECTIVE:Prevention of hearing impairment is important because it is difficult to recover from it. Epidemiological studies have examined the risk factors for hearing impairment; however, the association between dipstick proteinuria and hearing impairment has not been previously examined. This study aimed to clarify the association between dipstick proteinuria and hearing impairment. DESIGN:Cross-sectional study. SETTING:Office and factory workers from all over Japan. PARTICIPANTS:The total number of subjects was 7005. All were employees of the same company. Of these, we recruited 6192 subjects who underwent dipstick urine test and hearing test by audiometry in annual health check-ups (mean age 44.9 years, men 88.3%). PRIMARY OUTCOMES:Hearing tests were performed at two frequencies (1?kHz, 4?kHz) as prescribed by law in Japan. We defined the inability of subjects to respond to 30?dB at 1?kHz and/or 40?dB at 4?kHz as overall moderate hearing impairment. In addition, we defined moderate hearing impairment at 1?kHz (4?kHz) as an abnormal finding at 1?kHz (4?kHz). We examined the associations between degree of dipstick proteinuria and hearing impairment after adjustment for age, sex, body mass index, hypertension, diabetes mellitus, serum creatinine level and history of noisy work environment. RESULTS:Overall moderate hearing impairment was noted in 324 subjects (5.2%). Of these, 107 subjects (1.7%) had moderate hearing impairment at 1?kHz and 278 subjects (4.5%) at 4?kHz. Dipstick proteinuria was significantly associated with overall moderate hearing impairment, as well as moderate hearing impairment at both 1?kHz and 4?kHz. The prevalence of overall moderate hearing impairment among subjects with proteinuria ?2+ was 23.5%, while that among subjects without proteinuria was 5.2% (p<0.01). CONCLUSIONS:Dipstick proteinuria was associated with moderate hearing impairment in Japanese workers.

SUBMITTER: Umesawa M

PROVIDER: S-EPMC5961557 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Association between dipstick proteinuria and hearing impairment in health check-ups among Japanese workers: a cross-sectional study.

Umesawa Mitsumasa M Hara Mikako M Sairenchi Toshimi T Haruyama Yasuo Y Nagao Masanori M Matsushita Munehiro M Kobashi Gen G

BMJ open 20180514 5

<h4>Objective</h4>Prevention of hearing impairment is important because it is difficult to recover from it. Epidemiological studies have examined the risk factors for hearing impairment; however, the association between dipstick proteinuria and hearing impairment has not been previously examined. This study aimed to clarify the association between dipstick proteinuria and hearing impairment.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Office and factory workers from all over Japan.<h4>Pa ...[more]

PMID: 29764886

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Project description:Study objectiveTo evaluate the competency of trained health workers in detecting and managing hypertensive disorders of pregnancy during routine antenatal check-ups (ANCs) at primary care facilities in Bangladesh.Study design and settingsCross-sectional study; conducted in 26 primary care facilities.Outcome measuresAccurate diagnosis of the hypertensive disorders of pregnancy.MethodIn total 1560 ANC consultations provided by primary health workers, known as Family Welfare Visitors (FWVs), were observed using a structured checklist between October 2017 and February 2018. All consultations were reassessed by study physicians for validation.ResultOf the 'true' cases of gestational hypertension (n=32), pre-eclampsia (n=29) and severe pre-eclampsia (n=16), only 3%, 7% and 25%, respectively, were correctly diagnosed by FWVs. Per cent agreement for the diagnosed cases of any hypertensive disorders of pregnancy was 9% and kappa statistics was 0.50 (p value 0.0125). For identification of any hypertensive disorders by FWVs, sensitivity and positive predictive values were 14% and 50%, respectively. There was a moderate positive correlation between the blood pressure measurements taken by FWVs and study physicians. Only 27% of those who had 'some protein' in urine were correctly identified by FWVs. Women diagnosed with any of the hypertensive disorders of pregnancy by FWVs were more likely to be counselled on at least one danger sign of pre-eclampsia (severe headache, blurring of vision and upper abdominal pain) than those without any such diagnosis (41% vs 19%, p value 0.008). All four cases of severe pre-eclampsia diagnosed by FWVs were given a loading dose of intramuscular magnesium sulphate and three among them were referred to a higher facility.ConclusionThe FWVs should be appropriately trained on risk assessment of pregnant women with particular emphasis on accurately assessing the diagnostic criteria of hypertensive disorders of pregnancy and its management.

Dataset Information

Association between dipstick proteinuria and hearing impairment in health check-ups among Japanese workers: a cross-sectional study.

Publications

Association between dipstick proteinuria and hearing impairment in health check-ups among Japanese workers: a cross-sectional study.

Similar Datasets

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