Ontology highlight
ABSTRACT:
SUBMITTER: Simam J
PROVIDER: S-EPMC5963192 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Simam Joan J Rono Martin M Ngoi Joyce J Nyonda Mary M Mok Sachel S Marsh Kevin K Bozdech Zbynek Z Mackinnon Margaret M
BMC genomics 20180521 1
<h4>Background</h4>Gene copy number variants (CNVs), which consist of deletions and amplifications of single or sets of contiguous genes, contribute to the great diversity in the Plasmodium falciparum genome. In vitro studies in the laboratory have revealed their important role in parasite fitness phenotypes such as red cell invasion, transmissibility and cytoadherence. Studies of natural parasite populations indicate that CNVs are also common in the field and thus may facilitate adaptation of t ...[more]