Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5966244 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Zhang Yan Y Zhou Li-Ping LP Li Xiao-Li XL Zhao Yong-Jian YJ Ho Ming-Xian MX Qiu Zuo-Cheng ZC Zhao Dong-Feng DF Mok Daniel Kam-Wah DK Shi Qi Q Wang Yong-Jun YJ Wong Man-Sau MS
Oncotarget 20180319 36
Our previous study reported that the <i>in vitro</i> osteogenic effects of 8-prenylgenistein (8PG) were more potent than its parent compound genistein. This study aimed to evaluate the osteoprotective effects of 8PG in ovariectomized (OVX) mice as well as to characterize its estrogenic effects in uterus. Mature OVX mice were treated with phytoestrogen-free diet containing 8PG or genistein. Trabecular bone mass and most of the micro-structural parameters were ameliorated at the distal femoral met ...[more]