Ontology highlight
ABSTRACT:
SUBMITTER: Mastroeni D
PROVIDER: S-EPMC5967608 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Mastroeni Diego D Khdour Omar M OM Delvaux Elaine E Nolz Jennifer J Olsen Gary G Berchtold Nicole N Cotman Carl C Hecht Sidney M SM Coleman Paul D PD
Alzheimer's & dementia : the journal of the Alzheimer's Association 20161025 5
<h4>Introduction</h4>We have comprehensively described the expression profiles of mitochondrial DNA and nuclear DNA genes that encode subunits of the respiratory oxidative phosphorylation (OXPHOS) complexes (I-V) in the hippocampus from young controls, age matched, mild cognitively impaired (MCI), and Alzheimer's disease (AD) subjects.<h4>Methods</h4>Hippocampal tissues from 44 non-AD controls (NC), 10 amnestic MCI, and 18 AD cases were analyzed on Affymetrix Hg-U133 plus 2.0 arrays.<h4>Results< ...[more]