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Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?

ABSTRACT: A library of water-soluble dynamic single-chain polymeric nanoparticles (SCPN) was prepared using a controlled radical polymerisation technique followed by the introduction of functional groups, including probes at targeted positions. The combined tools of electron paramagnetic resonance (EPR) and Overhauser dynamic nuclear polarization (ODNP) reveal that these SCPNs have structural and surface hydration properties resembling that of enzymes.

SUBMITTER: Stals PJM

PROVIDER: S-EPMC5968450 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

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Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?

Stals Patrick J M PJM Cheng Chi-Yuan CY van Beek Lotte L Wauters Annelies C AC Palmans Anja R A ARA Han Songi S Meijer E W EW

Chemical science 20151208 3

A library of water-soluble dynamic single-chain polymeric nanoparticles (SCPN) was prepared using a controlled radical polymerisation technique followed by the introduction of functional groups, including probes at targeted positions. The combined tools of electron paramagnetic resonance (EPR) and Overhauser dynamic nuclear polarization (ODNP) reveal that these SCPNs have structural and surface hydration properties resembling that of enzymes. ...[more]

PMID: 29899925

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