Ontology highlight
ABSTRACT:
SUBMITTER: Leaf DE
PROVIDER: S-EPMC5969465 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Leaf David E DE Siew Edward D ED Eisenga Michele F MF Singh Karandeep K Mc Causland Finnian R FR Srivastava Anand A Alp Ikizler T T Ware Lorraine B LB Ginde Adit A AA Kellum John A JA Palevsky Paul M PM Wolf Myles M Waikar Sushrut S SS
Clinical journal of the American Society of Nephrology : CJASN 20180308 4
<h4>Background and objectives</h4>Dysregulated mineral metabolism is a common and potentially maladaptive feature of critical illness, especially in patients with AKI, but its association with death has not been comprehensively investigated. We sought to determine whether elevated plasma levels of the osteocyte-derived, vitamin D-regulating hormone, fibroblast growth factor 23 (FGF23), are prospectively associated with death in critically ill patients with AKI requiring RRT, and in a general coh ...[more]