Ontology highlight
ABSTRACT:
SUBMITTER: Pelaia C
PROVIDER: S-EPMC5971345 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Pelaia Corrado C Calabrese Cecilia C Vatrella Alessandro A Busceti Maria Teresa MT Garofalo Eugenio E Lombardo Nicola N Terracciano Rosa R Pelaia Girolamo G
BioMed research international 20180510
Asthma is a very frequent chronic airway disease that includes many different clinical phenotypes and inflammatory patterns. In particular, eosinophilic bronchial inflammation is often associated with allergic as well as nonallergic asthma. The most important cytokine involved in the induction, maintenance, and amplification of airway eosinophilia in asthma is interleukin-5 (IL-5), released by both T helper 2 (Th2) lymphocytes and group 2 innate lymphoid cells (ILC2). Hence, IL-5 and its recepto ...[more]