Ontology highlight
ABSTRACT:
SUBMITTER: Strong AL
PROVIDER: S-EPMC5973795 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Strong Amy L AL Semon Julie A JA Strong Thomas A TA Santoke Tatyana T TT Zhang Shijia S McFerrin Harris E HE Gimble Jeffrey M JM Bunnell Bruce A BA
Stem cells (Dayton, Ohio) 20121201 12
Adipose tissue maintains a subpopulation of cells, referred to as adipose-derived stromal/stem cells (ASCs), which have been associated with increased breast cancer tumorigenesis and metastasis. For ASCs to affect breast cancer cells, it is necessary to delineate how they mobilize and home to cancer cells, which requires mobilization and invasion through extracellular matrix barriers. In this study, ASCs were separated into four different categories based on the donor's obesity status and depot ...[more]