Ontology highlight
ABSTRACT:
SUBMITTER: Encinas G
PROVIDER: S-EPMC5976478 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Oncotarget 20180427 32
Breast cancer arising in very young patients may be biologically distinct; however, these tumors have been less well studied. We characterized a group of very young patients (≤ 35 years) for BRCA germline mutation and for somatic mutations in luminal (<i>HER2</i> negative) breast cancer. Thirteen of 79 unselected very young patients were <i>BRCA</i>1/2 germline mutation carriers. Of the non-<i>BRCA</i> tumors, eight with luminal subtype (<i>HER2</i> negative) were submitted for whole exome seque ...[more]