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Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator.

ABSTRACT: An interesting palladium-catalyzed carbonylative procedure for the synthesis of aromatic aldehydes from aryl iodides has been developed. By using propylphosphonic anhydride as the activator for formic acid, moderate to good yields of the corresponding aldehydes were produced with formic acid as the carbonyl and hydrogen donors. Interestingly, neither additional phosphine ligand nor inert gas protection is needed here.

SUBMITTER: Wu XF

PROVIDER: S-EPMC5976648 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator.

Wu Xiao-Feng XF

Scientific reports 20180530 1

An interesting palladium-catalyzed carbonylative procedure for the synthesis of aromatic aldehydes from aryl iodides has been developed. By using propylphosphonic anhydride as the activator for formic acid, moderate to good yields of the corresponding aldehydes were produced with formic acid as the carbonyl and hydrogen donors. Interestingly, neither additional phosphine ligand nor inert gas protection is needed here. ...[more]

PMID: 29849095

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