Ontology highlight
ABSTRACT:
SUBMITTER: Muqbil I
PROVIDER: S-EPMC5977111 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Muqbil Irfana I Azmi Asfar S AS Mohammad Ramzi M RM
Cancers 20180507 5
Pancreatic cancer is a deadly disease that is resistant to most available therapeutics. Pancreatic cancer to date has no effective drugs that could enhance the survival of patients once their disease has metastasized. There is a need for the identification of novel actionable drug targets in this unusually recalcitrant cancer. Nuclear protein transport is an important mechanism that regulates the function of several tumor suppressor proteins (TSPs) in a compartmentalization-dependent manner. Hig ...[more]