Ontology highlight
ABSTRACT:
SUBMITTER: Li XG
PROVIDER: S-EPMC5979389 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20180330 4
Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) and B-cell-specific Moloney murine leukemia virus insertion site 1 (BMI1) are markers of fast-cycling and quiescent intestinal stem cells, respectively. To determine the functions of these proteins in large animals, we investigated their effects on the proliferation of intestinal epithelial cells from pigs. Our results indicated that LGR5 and BMI1 are highly conserved proteins and that the pig proteins have greater homology with ...[more]