Ontology highlight
ABSTRACT:
SUBMITTER: Poppe D
PROVIDER: S-EPMC5980162 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Poppe Daniel D Doerr Jonas J Schneider Marion M Wilkens Ruven R Steinbeck Julius A JA Ladewig Julia J Tam Allison A Paschon David E DE Gregory Philip D PD Reik Andreas A Müller Christa E CE Koch Philipp P Brüstle Oliver O
Stem cells translational medicine 20180328 6
As a powerful regulator of cellular homeostasis and metabolism, adenosine is involved in diverse neurological processes including pain, cognition, and memory. Altered adenosine homeostasis has also been associated with several diseases such as depression, schizophrenia, or epilepsy. Based on its protective properties, adenosine has been considered as a potential therapeutic agent for various brain disorders. Since systemic application of adenosine is hampered by serious side effects such as vaso ...[more]