Ontology highlight
ABSTRACT:
SUBMITTER: Teiken K
PROVIDER: S-EPMC5985559 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Teiken Kristin K Kuehnel Mark M Rehkaemper Jan J Kreipe Hans H Laenger Florian F Hussein Kais K Jonigk Danny D
Clinical sarcoma research 20180604
Post-transplant smooth muscle tumors (PTSMTs) are rare mesenchymal neoplasms which occur after solid organ or haematopoietic stem cell transplantation. PTSMT typically consist of Epstein-Barr-virus (EBV)+ smooth muscle-like cells and show an intermediate malignancy. Their main occurrences are visceral organs, especially the liver, but intracranial appearances are described and associated with a poor prognosis. EBV drives the growth of PTSMT; however, the underlying molecular mechanisms still rem ...[more]