Ontology highlight
ABSTRACT:
SUBMITTER: Buddington RK
PROVIDER: S-EPMC5986515 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Buddington Randal K RK Howard Scott C SC Lee Harold W HW Buddington Karyl K KK
Nutrients 20180518 5
Growth after preterm birth is an important determinant of long-term outcomes. Yet, many preterm infants suffer ex utero growth retardation. We evaluated effects of leucine and the metabolite, β-hydroxy β-methylbutyrate (HMB) on growth of preterm pigs, a previously-validated translational model for preterm infants. After 48 h of parenteral nutrition preterm pigs were fed for 6 to 7 days isocaloric formulas with different levels of protein (50 or 100 g/L) with leucine (10 g/L, 76 mM) or HMB (at 1. ...[more]