Ontology highlight
ABSTRACT:
SUBMITTER: Gaut D
PROVIDER: S-EPMC5993360 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Gaut Daria D Sasine Joshua J Schiller Gary G
Leukemia research reports 20180416
Although rare, secondary clonal hematologic neoplasia may occur after successful therapy for acute promyelocytic leukemia (APL). These secondary clonal events may be considered therapy-related, but may also be due to an underlying background of clonal hematopoiesis from which both malignancies may develop. In this manuscript, we describe two patients with secondary clones after APL therapy characterized in one patient by deletion of chromosome 11q23 and, in the other, by monosomy of chromosome 7 ...[more]