Ontology highlight
ABSTRACT:
SUBMITTER: Schrepf A
PROVIDER: S-EPMC5993749 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Nature communications 20180608 1
It is unknown how chronic inflammation impacts the brain. Here, we examined whether higher levels of peripheral inflammation were associated with brain connectivity and structure in 54 rheumatoid arthritis patients using functional and structural MRI. We show that higher levels of inflammation are associated with more positive connections between the inferior parietal lobule (IPL), medial prefrontal cortex, and multiple brain networks, as well as reduced IPL grey matter, and that these patterns ...[more]