Ontology highlight
ABSTRACT:
SUBMITTER: Ceinos RM
PROVIDER: S-EPMC5993827 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Ceinos Rosa Maria RM Frigato Elena E Pagano Cristina C Fröhlich Nadine N Negrini Pietro P Cavallari Nicola N Vallone Daniela D Fuselli Silvia S Bertolucci Cristiano C Foulkes Nicholas S NS
Scientific reports 20180608 1
Light represents the principal signal driving circadian clock entrainment. However, how light influences the evolution of the clock remains poorly understood. The cavefish Phreatichthys andruzzii represents a fascinating model to explore how evolution under extreme aphotic conditions shapes the circadian clock, since in this species the clock is unresponsive to light. We have previously demonstrated that loss-of-function mutations targeting non-visual opsins contribute in part to this blind cloc ...[more]