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Hypoglycaemia in diabetes: do we think enough of the cause? An observational study on prevalence and causes of hypoglycaemia among patients with type 2 diabetes in an out-patient setting in Sri Lanka.


ABSTRACT:

Background

Hypoglycaemia is a feared experience for people with diabetes. We aimed to study the prevalence and causes of hypoglycaemia among Sri Lankans with diabetes.

Methods

One thousand patients with diabetes attending a private sector diabetic clinic were interviewed using a structured questionnaire. Hypoglycaemic episodes within the preceding month were inquired and severity was graded according to clinical features and/or capillary blood glucose levels.

Results

Mean age 55.0 years (±?12.5), 58.6% were males, mean diabetes duration 10.6 years (±?8.1), mean FPG 7.48 mmol/l (±?2.79) and mean HbA1c 7.82% (±?1.71) (62 mmol/mol). Of them, 26.1%. (mild 20.7%, moderate 3.9%, and severe 1.5%) experienced symptomatic hypoglycaemia. Sudden change diet (46.7%), unaccustomed exercise (15.7%) and increase in antihyperglycaemic therapy dosage (14.9%) were the recognized causes. Cause was not recognized by 16.3%. Non-prescribed native food items accounted for hypoglycaemia in 16.9% of patients (Momordica charantia 54.5%, Costus speciosus 52.3%, Salacia prinoides 11.4%, Coccinia grandis 6.8%, Adenanthera pavonina 4.5%). Severity of hypoglycaemia was positively correlated to age and duration of diabetes but not to HbA1C.

Conclusion

Hypoglycaemia is common among patients with diabetes. Patients need advice on regular diet and exercise. Consumption of non-prescribed native foods should be considered as a possible cause.

SUBMITTER: Dissanayake HA 

PROVIDER: S-EPMC5994038 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Publications

Hypoglycaemia in diabetes: do we think enough of the cause? An observational study on prevalence and causes of hypoglycaemia among patients with type 2 diabetes in an out-patient setting in Sri Lanka.

Dissanayake H A HA   Keerthisena G S P GSP   Gamage K K K KKK   Liyanage J H JH   Ihalagama I R H S IRHS   Wijetunga W M U A WMUA   Tillekaratne T A D TAD   Katulanda G W GW   Katulanda P P  

BMC endocrine disorders 20180608 1


<h4>Background</h4>Hypoglycaemia is a feared experience for people with diabetes. We aimed to study the prevalence and causes of hypoglycaemia among Sri Lankans with diabetes.<h4>Methods</h4>One thousand patients with diabetes attending a private sector diabetic clinic were interviewed using a structured questionnaire. Hypoglycaemic episodes within the preceding month were inquired and severity was graded according to clinical features and/or capillary blood glucose levels.<h4>Results</h4>Mean a  ...[more]

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