Identifying behavioral phenotypes for childhood obesity.
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ABSTRACT:
SUBMITTER: Kral TVE
PROVIDER: S-EPMC5994376 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Identifying behavioral phenotypes for childhood obesity.
Kral Tanja V E TVE Moore Reneé H RH Chittams Jesse J Jones Elizabeth E O'Malley Lauren L Fisher Jennifer O JO
Appetite 20180427
Existing programs which aim to prevent and treat childhood obesity often do not take into account individual variation and the underlying mechanisms that impact child eating behavior. Individual differences in children's appetitive traits have been shown to appear as early as during infancy and become more pronounced as children grow older and become more exposed to the obesogenic food environment. Differences in genetic predispositions interacting with factors in children's early environment ac ...[more]
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Project description:In the past few decades, the prevalence of overweight and obesity has sharply increased in children and adolescents. Childhood obesity life are associated with increased risk of cardiovascular disease (CVD), diabetes mellitus, metabolic syndrome, sleep disturbances and certain cancers in adulthood. Childhood obesity has become a serious global public health challenge. Long noncoding RNAs (lncRNAs) have an important role in adipose tissue function and energy metabolism homeostasis, and abnormalities may lead to obesity. We used microarrays to detail the differential expression profile of lncRNAs and mRNAs in obese children compared with non-obese children.
2018-06-14 | GSE104815 | GEO