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Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel.

ABSTRACT: This data article presents datasets associated with the research article entitled "Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer" (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes.

SUBMITTER: Fong ELS

PROVIDER: S-EPMC5996264 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel.

Fong Eliza Li Shan ELS Toh Tan Boon TB Lin Quy Xiao Xuan QXX Liu Zheng Z Hooi Lissa L Rashid Masturah Bte Mohd Abdul MBMA Benoukraf Touati T Chow Edward Kai-Hua EK Huynh The Hung TH Yu Hanry H

Data in brief 20180317

This data article presents datasets associated with the research article entitled "Generation of matched patient-derived xenograft <i>in vitro-in vivo</i> models using 3D macroporous hydrogels for the study of liver cancer" (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate <i>in vitro</i> counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular f ...[more]

PMID: 29900213

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