Ontology highlight
ABSTRACT:
SUBMITTER: Ram DR
PROVIDER: S-EPMC5997355 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Ram Daniel R DR Manickam Cordelia C Hueber Brady B Itell Hannah L HL Permar Sallie R SR Varner Valerie V Reeves R Keith RK
PLoS pathogens 20180531 5
Natural killer (NK) cells classically typify the nonspecific effector arm of the innate immune system, but have recently been shown to possess memory-like properties against multiple viral infections, most notably CMV. Expression of the activating receptor NKG2C is elevated on human NK cells in response to infection with CMV as well as HIV, and may delineate cells with memory and memory-like functions. A better understanding of how NKG2C+ NK cells specifically respond to these pathogens could be ...[more]