Oxidative and endoplasmic reticulum stress in respiratory disease.
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ABSTRACT:
SUBMITTER: Chen AC
PROVIDER: S-EPMC5999202 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Oxidative and endoplasmic reticulum stress in respiratory disease.
Chen Alice C-H AC Burr Lucy L McGuckin Michael A MA
Clinical & translational immunology 20180613 6
Oxidative stress and endoplasmic reticulum (ER) stress are related states that can occur in cells as part of normal physiology but occur frequently in diseases involving inflammation. In this article, we review recent findings relating to the role of oxidative and ER stress in the pathophysiology of acute and chronic nonmalignant diseases of the lung, including infections, cystic fibrosis, idiopathic pulmonary fibrosis and asthma. We also explore the potential of drugs targeting oxidative and ER ...[more]
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