Ontology highlight
ABSTRACT:
SUBMITTER: Bianchi S
PROVIDER: S-EPMC6003225 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Bianchi Sarah S Rogala Kacper B KB Dynes Nicola J NJ Hilbert Manuel M Leidel Sebastian A SA Steinmetz Michel O MO Gönczy Pierre P Vakonakis Ioannis I
Molecular biology of the cell 20180124 6
Centrioles are microtubule-based organelles that organize the microtubule network and seed the formation of cilia and flagella. New centrioles assemble through a stepwise process dependent notably on the centriolar protein SAS-5 in <i>Caenorhabditis elegans</i> SAS-5 and its functional homologues in other species form oligomers that bind the centriolar proteins SAS-6 and SAS-4, thereby forming an evolutionarily conserved structural core at the onset of organelle assembly. Here, we report a novel ...[more]