Dataset Information
Hypervalent iodine(III)-mediated decarboxylative acetoxylation at tertiary and benzylic carbon centers.
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ABSTRACT:
SUBMITTER: Kiyokawa K
PROVIDER: S-EPMC6009488 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Hypervalent iodine(III)-mediated decarboxylative acetoxylation at tertiary and benzylic carbon centers.
Beilstein journal of organic chemistry 20180515
The decarboxylative acetoxylation of carboxylic acids using a combination of PhI(OAc)<sub>2</sub> and I<sub>2</sub> in a CH<sub>2</sub>Cl<sub>2</sub>/AcOH mixed solvent is reported. The reaction was successfully applied to two types of carboxylic acids containing an α-quaternary and a benzylic carbon center under mild reaction conditions. The resulting acetates were readily converted into the corresponding alcohols by hydrolysis. ...[more]