Dataset Information

Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment.

ABSTRACT:

Objectives

To assess the feasibility of delivering and evaluating a lifestyle programme for patients with colorectal cancer undergoing potentially curative treatments.

Study design

Non-randomised feasibility trial.

Setting

National Health Service (NHS) Tayside.

Participants

Adults with stage I-III colorectal cancer.

Intervention

The programme targeted smoking, alcohol, physical activity, diet and weight management. It was delivered in three face-to-face counselling sessions (plus nine phone calls) by lifestyle coaches over three phases (1: presurgery, 2: surgical recovery and 3: post-treatment recovery).

Primary outcome

Feasibility measures (recruitment, retention, programme implementation, achieved measures, fidelity, factors affecting protocol adherence and acceptability).

Secondary outcomes

Measured changes in body weight, waist circumference, walking and self-reported physical activity, diet, smoking, alcohol intake, fatigue, bowel function and quality of life.

Results

Of 84 patients diagnosed, 22 (26%) were recruited and 15 (18%) completed the study. Median time for intervention delivery was 5.5?hours. Coaches reported covering most (>70%) of the intervention components but had difficulties during phase 2. Evaluation measures (except walk test) were achieved by all participants at baseline, and most (<90%) at end of phase 2 and phase 3, but <20% at end of phase 1. Protocol challenges included limited time between diagnosis and surgery and the presence of comorbidities. The intervention was rated highly by participants but limited support from NHS staff was noted. The majority of participants (77%) had a body mass index>25?kg/m² and none was underweight. Physical activity data showed a positive trend towards increased activity overall, but no other changes in secondary outcomes were detected.

Conclusions

To make this intervention feasible for testing as a full trial, further research is required on (a) recruitment optimisation, (b) appropriate assessment tools, (c) protocols for phase 2 and 3, which can build in flexibility and (d) ways for NHS staff to facilitate the programme.

Trial registration number

ISRCTN52345929; Post-results.

SUBMITTER: Macleod M

PROVIDER: S-EPMC6009630 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Publications

Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment.

Macleod Maureen M Steele Robert J C RJC O'Carroll Ronan E RE Wells Mary M Campbell Anna A Sugden Jacqui A JA Rodger Jackie J Stead Martine M McKell Jennifer J Anderson Annie S AS

BMJ open 20180606 6

<h4>Objectives</h4>To assess the feasibility of delivering and evaluating a lifestyle programme for patients with colorectal cancer undergoing potentially curative treatments.<h4>Study design</h4>Non-randomised feasibility trial.<h4>Setting</h4>National Health Service (NHS) Tayside.<h4>Participants</h4>Adults with stage I-III colorectal cancer.<h4>Intervention</h4>The programme targeted smoking, alcohol, physical activity, diet and weight management. It was delivered in three face-to-face counse ...[more]

PMID: 29880567

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Dataset Information

Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment.

Objectives

Study design

Setting

Participants

Intervention

Primary outcome

Secondary outcomes

Results

Conclusions

Trial registration number

Publications

Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment.

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