Ontology highlight
ABSTRACT:
SUBMITTER: Lucas SEM
PROVIDER: S-EPMC6010250 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Lucas Sionne E M SEM Zhou Tiger T Blackburn Nicholas B NB Mills Richard A RA Ellis Jonathan J Leo Paul P Souzeau Emmanuelle E Ridge Bronwyn B Charlesworth Jac C JC Lindsay Richard R Craig Jamie E JE Burdon Kathryn P KP
PloS one 20180620 6
Many genes have been suggested as candidate genes for keratoconus based on their function, their proximity to associated polymorphisms or due to the identification of putative causative variants within the gene. However, very few of these genes have been assessed for rare variation in keratoconus more broadly. In contrast, VSX1 and SOD1 have been widely assessed, however, the vast majority of studies have been small and the findings conflicting. In a cohort of Australians of European descent, co ...[more]